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The cellular mechanism by which the releasing hormones affect GH secretion from the somatotrope requires specific signal transduction systems (cAMP and/or calcium influx and/or mobilization of intracellular calcium) and/ or tyrosine kinase(s) and/or nitric oxide (NO)/cGMP

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Seahorse metabolic extracellular flux profiling CD34 + AML cells or human leukemia cell lines (MOLM-13 and KG-1) cocultured with vehicle (phosphate-buffered saline, PBS without EVs) or EV AML were seeded in 24-well plates (~500.000 cells/well)

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